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Rudolf Fittig |
*6.12.1835 19.11.1910
in Tübingen 1870-1876 |
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back to History
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Rudolf
Fittig, (1835-1910), German chemist, was born at Hamburg on 6
December 1835. He studied chemistry at Göttingen, graduating as
Ph.D. with a dissertation on acetone in 1858. He subsequently held
several appointments at Göttingen, being privat dozent (1860), and
extraordinary professor (1870). In 1870 he obtained the chair at
Tübingen, and in 1876 that at Strassburg, where the laboratories
were erected from his designs. Fittig's researches are entirely in
organic chemistry, and cover an exceptionally wide field. The
aldehydes and ketones provided material for his earlier work. He
observed that aldehydes and ketones may suffer reduction in
neutral, alkaline, and sometimes acid solution to secondary and
tertiary glycols, substances which he named pinacones; and also
that certain pinacones when distilled with dilute sulphuric acid
gave compounds, which he named pinacolines. The unsaturated acids
also received much attention, and he discovered the internal
anhydrides of oxyacids, termed lactones. In 1863 he introduced the
reaction known by his name. In 1855 Adolph Wurtz had shown that
when sodium acted upon alkyl iodides, the alkyl residues combined
to form more complex hydrocarbons; Fittig developed this method by
showing that a mixture of an aromatic and alkyl haloid, under
similar treatment, yielded homologues of benzene. His
investigations on Perkins reaction led him to an explanation of
its mechanism which appeared to be more in accordance with the
facts. The question, however, is one of much difficulty, and the
exact course of the reaction appears to await solution. These
researches incidentally solved the constitution of coumarin, the
odoriferous principle of woodruff. Fittig and Erdmann's
observation that phenyl isocrotonic acid readily yielded a-naphthol
by loss of water was of much importance, since it afforded
valuable evidence as to the constitution of naphthalene. They also
investigated certain hydrocarbons occurring in the high boiling
point fraction of the coal tar distillate and solved the
constitution of phenanthrene. We also owe much of our knowledge of
the alkaloid piperine to Fittig, who in collaboration with Ira
Remsen established its constitution in 1871. Fittig has published
two widely used textbooks; be edited several editions of Wohler's
Grundriss der organischen Chemie (11th ed., 1887) and wrote an
Anorganische Chemie (1st ed., 1872; 3rd, 1882). His researches
have been recognized by many scientific societies and
institutions, the Royal Society awarding him the Davy medal in
1906. He died on 19 November 1910.
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Wurtz-Fittig Reaction

B.
Tollens, R. Fittig,
Ann.
131,
303 (1864)
R.
Fittig, J. König, Ann.
144,
277 (1867) |
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